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Tramadol is a prescription opioid painkiller for moderate to severe pain, acting on the central nervous system by mimicking natural painkillers and affecting serotonin/norepinephrine. Available as generics and brands (Ultram, Tramal), it comes in immediate-release and slow-release forms, sometimes combined with acetaminophen (Ultracet). It's a controlled substance due to misuse potential, carries risks like dependence, and has side effects including dizziness, nausea, constipation, and sleepiness, requiring careful use under medical supervision.